Structural Biology

Structural Image of Human Lungs

A number of our researchers are engaged in studying structural and biochemical properties of proteins and the complexes they form, to help us better understand how these proteins contribute to biological processes. Structural biology combines technologies from molecular biology, biochemistry and biophysics to elucidate the three-dimensional structures of biological macromolecules, which ultimately affect their function. Scientists in this area use technologies such as crystallography, nuclear magnetic resonance (NMR) spectroscopy and cryo-electron microscopy (cryo-EM) to solve structures and gain novel biological insights.

Examples of specific research topics include:

  • Cancer Signaling
  • Cryo-EM
  • Membrane proteins
  • Protein Complexes
  • Protein Engineering
  • Protein Folding
  • Protein Misfolding Disease
  • Protein Structure
  • Signal Transduction
  • X-ray Crystallography

View Medical Biophysics faculty working in this area.