The functioning of a biological system, which can be as small as individual organelles within a cell or as large as the whole of the human body, is closely linked to the spatial arrangement of its parts. Imaging technology provides a means to identify and understand these spatial patterns, aiding both in medical diagnosis and understanding healthy development across the lifespan. MBP researchers are working to develop new imaging technologies as well as new medical applications of existing imaging technologies. Some of the technology areas that are active within the department include magnetic resonance, ultrasound, magnetoencephalography, X-ray and optical techniques applied to a range of organ systems and across a range of diseases. Depending on the stage of technology development and the ultimate application, these projects may include investigations of the fundamental physical principles, engineering of devices and contrast agents, studies in model organisms, or clinical studies in humans.
Examples of specific research topics include:
- Imaging methods and hardware for specific organs including the brain, heart, and lung
- Imaging across the lifespan from fetal development to aging
- Imaging applications across all scales, from microscopic to macroscopic
- Imaging technologies customized for specific model organisms such as mice and rats
- Development of imaging contrast mechanisms that are specific to tissue microstructure, organisation, metabolism, blood flow, motion, or specific biomolecules