New Publication from Dr. Hansen He and Dr. Stanley Liu
MBP researchers Dr. Hansen He, Dr. Stanley Liu and a team of collaborators have recently released a new Journal of Translational Medicine paper entitled 'Circulating miRNAs as Non-invasive Biomarkers to Predict Aggressive Prostate Cancer After Radical Prostatectomy'.
The goal of this research was to identify circulating microRNA that could independently predict prostate cancer patient risk stratification after radical prostatectomy. For this study, seventy-eight prostate cancer patients who had undergone radical protesectomy were recruited. Blood samples were collected simultaneously for PSA testing and miRNA analysis using NanoString nCounter technology. Patients were stratified into high- and low-risk categories based on Gleason score, pathological T stage, surgical margin status, and diagnostic PSA: patients with Gleason ≥ 8; pT3a and positive margin; pT3b and any margin; or diagnostic PSA > 20 µg/mL were classified as high-risk (n = 44) and all other patients were classified as low-risk (n = 31).
Read a commentary by the authors