Quantitative Magnetic Resonance Imaging - Mechanisms of Tissue Contrast
The goal of our studies is to develop magnetic resonance imaging (MRI) methods to improve specificity and sensitivity of non-invasive image methods in characterizing tissue pathology. We use MRI both in animal models of disease and in patients. In particular we use MRI to evaluate tissue microstructure and metabolism in variety of different disorders. Our research interest include, but are not limited to:
- Optimizing MRI methods to predict tumour response to treatment,
- Applying new imaging technology for MRI-Linac and MRI-brachytherapy systems,
- Developing MRI methods to assess radiation dose,
- Testing new multimodal contrast agents for improved specificity of cancer diagnosis,
- Characterizing new models of spinal cord injury and testing new treatments for SCI,
- Understanding the mechanisms of tissue damage in central nervous system,
- Evaluating brain metabolism using magnetic resonance spectroscopy (MRS) in response to microbiotic treatment in animal models of depression.
Our group has an access to following facilities:
- 3 T MRI human systems (GE, Phillips, Siemens),
- 7 T MRI animal scanner (Bruker),
- Animal PET/SPECT/CT system (MILabs),
- Multiphoton in vivo microscope (Olympus)
Our group consists of one PhD student, three post-doctoral fellows and three research associates (biology and physics).
For further information, please visit Dr. Greg Stanisz profile at Sunnybrook.