We are pleased to announce the appointment of Dr. Grace Egan, Assistant Professor, to the Department of Medical Biophysics.
Dr. Egan is an Assistant Professor at the University of Toronto and a clinician-scientist and staff oncologist at The Hospital for Sick Children. Her laboratory integrates transcriptomic analysis with functional genomic approaches and patient-derived leukemia models to understand how the distinct developmental and molecular biology of paediatric and adolescent/young adult AML creates therapeutic vulnerabilities. A central focus of her research is nucleocytoplasmic transport, the tightly regulated movement of proteins and RNA between the nucleus and cytoplasm, and how its dysregulation intersects with ribosome biogenesis and DNA repair to support leukemia growth, survival, and treatment resistance. Given the molecular heterogeneity of paediatric and AYA AML, her group aims to distinguish dependencies that are broadly shared across the disease from those that are specific to particular genomic subtypes, with the ultimate goal of translating this biology into biomarkers and therapeutic strategies that improve outcomes for children, adolescents, and young adults with high-risk AML.
Please join us in welcoming Dr. Egan to the department.