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MBP 1022H - Molecular and Cellular Biology for the Physical Scientist

  Section code: F  
  Coordinator: Jonathan Rast
Sunnybrook, Rm S-234
  Telephone: 416-480-5195
  Email: Dr. Jonathan Rast's email address
  Time: Wednesdays, 9:00 – 11:00 a.m.
  Location:

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue
Dembo Auditorium (Room TB62 basement level T-wing), Jenkins Auditorium (TB21), or Harrison Hall (EG21).

Please refer to the lecture schedule below for the location on a particular date.

  Course Length: Sept. 21 - Dec 14, 2011
  Evaluation

1 midterm exam
1 oral assignment
1 written take-home exam

    Lecture Schedule

Course Description: This course introduces physical scientists to the basic concepts of cell and molecular biology including structure of nucleic acids (DNA & RNA) and proteins, DNA replication, transcription, translation, genetics, regulation of gene expression, cell growth and differentiation, basic cancer biology and immunology. The course will stress breadth rather than depth and is designed to introduce physical scientists whose research impinges on biology to the concepts and methodologies of molecular biology. Although there are no pre-requisites for the course, it will be assumed that students have a background in biology equivalent to high school biology. If you have taken biology beyond a second year undergraduate level you should not take this course. This is a graduate course that is taught at an accelerated pace and requires considerable out of class time to review the required material.

Textbook: All required material will be covered with lecture and student in-class presentations. However, we suggest Molecular Biology of the Cell 5th Edition, Alberts et al, (2008) as a reference. (an older version of this text is available online through NCBI at http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4.TOC&depth=2).

Teaching Format:Each lecture is 1.5-2 hr.  Handouts of the instructors’ presentations will be available at the beginning of each lecture. The first five lectures cover basic subjects in molecular and cell biology.  The remaining six sessions will be centered on student presentations of research papers in selected areas of molecular and cell biology.

All classes are held at Sunnybrook Health Sciences Centre 2075 Bayview, Avenue. Please see the schedule below for classrooms. Classes are on Wednesdays between 9:00am to 11:00am. 

Lecture Schedule 2011

Date
Lecture #
Instructor
Location
Assignment
Topic

Sep-21

1

JR

TB21

Chapter 1&2

Overview of mol. biology, molecules of life

Sep-28

2

JR

TB62

Chapter 4&5

DNA &RNA structure, DNA replication

Oct-05

3

JR
EG21 Chapter 3 Proteins

Oct-12

4

JR

TB62

Chapter 6

Transcription & Translation

Oct-19

5

JR

TB62

Chapter 8

methods in molecular biology

Oct-26

6

JR

TB62

 

regulation of gene expression

Nov-2

 

TB21

 

MIDTERM

Nov-9

7

JR

TB62

 

cell biology

Nov-16

8

JR

TB62

 

Development

Nov-23

9

JR

TB62

 

Immunology

Nov-30

10

TBA

TB62

 

Cell Signaling

    Dec-7

11

TBA

TB21

 

Cancer

Dec-14

JR

TB62

 

FINAL

 

 

 
Last Updated: September 28, 2011 All contents Copyright © 1995 - 2011, Department of Medical Biophysics. All Rights Reserved.