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Cellular and Molecular Biology


Translational Medicine:

  • Adamson, Lee., at Mount Sinai Hospital
  • Archer, Michael C., at MSB
    Molecular carcinogenesis: the goal of this research program is to understand at the cellular and molecular level the mechanisms involved in th e causation of cancer.
  • Barber, Dwayne L., at OCI
    Signal Transduction in Hematopoiesis
  • Boyd, Norman F., at OCI
    Breast Cancer: Epidemiology and Prevention.
  • Bristow, Rob, at OCI
  • Danska, Jayne, at TMDT
  • Done, Susan, at OCI
  • Gallie, Brenda, at OCI
  • Guha, Abihijit , at HSC
  • Hedley, David W., at OCI
    Interest is trying to understand why cancer patients develop resistance to chemotherapy, and to this end his laboratory develops basic research methods for studying drug resistance phenotypes that can be applied to human biopsy material. Laboratory methods are heavily based on advanced flow and image cytometry techniques.
  • Hill, Richard P., at OCI
    Predictive assays of response of tumors to radiation treatment, studies of the metastatic potential of tumor cells.
  • Hogg, David, at MSB
    Molecular Genetics of Germ Cell Tumours and Cell Cycle Regulation.
  • Hudson, Thomas, at TMDT
  • Kamel-Reid, Suzanne, at OCI
  • Keller, Gordon, at TMDT
  • Kerbel, Robert S., at SHSC
    Tumor-host tissue interactions in malignant tumor progression: growth factors involved in metastasis; basis of acquired "multicellular" drug resistance in solid tumors; tumor angiogenesis.
  • Koch, Anne, at OCI
    DNA damage signaling, repair and cancer
  • Liu, Fei-Fei, at OCI
    I. Intracellular Ph Regulation and Thermosensitivity.
    II. Factors Predicting Treatment Response in Human Nasopharyngeal Carcinoma
  • Liu, Geoffrey, at OCI
  • Mak, Tak Wah, at AMDI/OCI
    Molecular biology of T cell antigen receptors: AIDS retrovirus, leukemia, T cell differentiation, host genetics in leukemia virus.
  • Malkin, David, at HSC
    The Molecular Biology of Cell Cycle Regulation in the Li-Fraumeni Familial Cancer Syndrome.
  • Marsden, Philip A., at MSB
    Endothelial Cells in Health and Disease
  • Martin, Lisa, at OCI
  • Medin, Jeffrey A., at Canadian Blood Services Building
  • Messner, Hans A., at OCI
    Directs the clinical Bone Marrow Transplant (BMT) program. One of the major goals is to understand mechanisms that lead to the control of hemopoietic malignancies by BMT. This is approached in clincal and laboratory studies.
  • Minden, Mark D., at OCI
    Regulatory mechanisms in human leukemia: identification and isolation of human leukemic transforming genes.
  • Minkin, Salomon, at OCI
    Statistical methods for the analysis of counts and binary data generated by cancer research.
  • Penn, Linda J. Z., at OCI
    Exploiting Molecular Oncology To Trigger Tumor Cell Death
  • Rottapel, Rob, at OCI
    Signal Transduction Pathways in Lymphocytes, mechanisms of autoimmunity and cancer.
  • Schimmer, Aaron, at OCI
    Translational apoptosis
  • Schuh, Andre C., at OCI
    Haematopoietic and Endothelial Development.
  • Spaner, David, at SHSC
  • Squire, Jeremy, at OCI
    Molecular Cytogenetics of Solid Tumours and Chromosomal Instability in Cancer
  • Tannock, Ian, at OCI
    Biology and experimental therapy of solid tumors: biological properties of solid tumors, influence of environmental factors on cell membrane exchange mechanisms and susceptibility of therapeutic attack.
  • Tritchler, David, at OCI
    Statistical Methods for Genetic Analysis.
  • Trudel, Suzanne, at OCI
    Molecular Targeted Therapy for the Treatment of Multiple Myeloma
  • Tsao, Ming, at OCI
    Molecular biology and pathogenesis of lung and pancreatic cancers.
  • Wells, Richard, at SHSC
    Nuclear Receptors in Normal and Malignant Haematopoiesis
  • Wong, Shun, at SHSC
    Response of the Central Nervous System to Ionizing Radiation.
  • Woo, Minna, at OCI
    Tissue-specific Molecular Determinants of Survival, Apoptosis and Metabolism

Advanced Medical Discovery Institute (AMDI), Hospital for Sick Children (HSC), Medical Sciences Building (MSB), Ontario Cancer Institute (OCI), Sunnybrook Health Sciences Centre (SHSC), Toronto Medical Discovery Tower (TMDT)

 
Last Updated: September 9, 2011 All contents Copyright © 1995 - 2011, Department of Medical Biophysics. All Rights Reserved.