• Adamson, Lee., at Mount Sinai Hospital
• Archer, Michael C., at MSB
  Molecular carcinogenesis: the goal of this research program is to understand at the cellular and molecular level the mechanisms involved in th e causation of cancer.
• Attisano, Liliana, at Terrence Donnelly CCBR
• Aubin, Jane, at MSB
• Barber, Dwayne L., at OCI
  Signal Transduction in Hematopoiesis
• Ben-David, Yaacov, at SHSC
  Oncogenes involved in leukemia: molecular mechanisms underlying evolution of erythroleukemia induced by Friend virus.
• Boyd, Norman F., at OCI
  Breast Cancer: Epidemiology and Prevention.
• Bristow, Rob, at OCI
• Czarnota, Gregory, at SHSC
• Danska, Jayne, at TMDT
• Done, Susan, at OCI
• Dumont, Dan, at SHSC
  Research on learning how development occurs in the cardiovascular system of the mouse embryo. Signals on a molecular level tell genes when to turn on and off, thus controlling the pattern of cells which determine the vascular system. Understanding the development control in the mouse embryo should provide insight into the control of tumor growth and progression.
• Filmus, Jorge, at SHSC
  Molecular basis of tumor progression: effects of oncogenes and tumor suppressor genes on growth and cell adhesion in colorectal and breast tumors.
• Gallie, Brenda, at OCI
• Guha, Abihijit , at HSC
• Hakem, Razqallah, at OCI
  Molecular Mechanisms of Apoptosis and DNA Damage Repair in Animal Models
• Hedley, David W., at OCI
  Interest is trying to understand why cancer patients develop resistance to chemotherapy, and to this end his laboratory develops basic research methods for studying drug resistance phenotypes that can be applied to human biopsy material. Laboratory methods are heavily based on advanced flow and image cytometry techniques.
• Hill, Richard P., at OCI
  Predictive assays of response of tumors to radiation treatment, studies of the metastatic potential of tumor cells.
• Hogg, David, at MSB
  Molecular Genetics of Germ Cell Tumours and Cell Cycle Regulation.
• Hudson, Thomas, at TMDT
• Iscove, Norman N., at TMDT
  Genes controlling self-renewal and differentiation in normal and leukemic hemopoietic stem cells.
• Jurisica, Igor, at TMDT
• Kamel-Reid, Suzanne, at OCI
• Keller, Gordon, at TMDT
• Kerbel, Robert S., at SHSC
  Tumor-host tissue interactions in malignant tumor progression: growth factors involved in metastasis; basis of acquired "multicellular" drug resistance in solid tumors; tumor angiogenesis.
• Khokha, Rama, at OCI
• Koch, Anne, at OCI
  DNA damage signaling, repair and cancer
• Letarte, Michelle, at HSC
• Liu, Fei-Fei, at OCI
  I. Intracellular Ph Regulation and Thermosensitivity.
  II. Factors Predicting Treatment Response in Human Nasopharyngeal Carcinoma
• Liu, Geoffrey, at OCI
• Mak, Tak Wah, at AMDI/OCI
  Molecular biology of T cell antigen receptors: AIDS retrovirus, leukemia, T cell differentiation, host genetics in leukemia virus.
• Malkin, David, at HSC
  The Molecular Biology of Cell Cycle Regulation in the Li-Fraumeni Familial Cancer Syndrome.
• Manoukian, Armen, at OCI
  Isolation and Characterization of the Components of Wnt Signaling Pathway(s)
• Marsden, Philip A., at MSB
  Endothelial Cells in Health and Disease
• Martin, Lisa, at OCI
• McGlade, Jane, at TMDT/HSC
  Signal transduction pathways in normal development, cell function and cancer.
• Medin, Jeffrey A., at Canadian Blood Services Building
• Messner, Hans A., at OCI
  Directs the clinical Bone Marrow Transplant (BMT) program. One of the major goals is to understand mechanisms that lead to the control of hemopoietic malignancies by BMT. This is approached in clincal and laboratory studies.
• Minden, Mark D., at OCI
  Regulatory mechanisms in human leukemia: identification and isolation of human leukemic transforming genes.
• Neel, Ben, at TMDT
• Ohashi, Pamela S., at OCI
  T lymphocyte development, activation and tolerance as applied to autoimmune disease and tumor surveillance.
• Okada, Hitoshi, at AMDI
• Paige, Chris, at OCI
• Penn, Linda J. Z., at OCI
  Exploiting Molecular Oncology To Trigger Tumor Cell Death
• Puri, Mira, at OTHER
  Molecular Genetics of Mammalian Vascular and Hematopoietic Development
• Raught, Brian, TMDT
• Rottapel, Rob, at OCI
  Signal Transduction Pathways in Lymphocytes, mechanisms of autoimmunity and cancer.
• Schimmer, Aaron, at OCI
  Translational apoptosis
• Schuh, Andre C., at OCI
  Haematopoietic and Endothelial Development.
• Spaner, David, at SHSC
• Squire, Jeremy, at OCI
  Molecular Cytogenetics of Solid Tumours and Chromosomal Instability in Cancer
• Stambolic, Vuk, at OCI
  Signal Transduction and Cancer: Regulation of Cellular Proliferation, Survival and Apoptosis
• Tannock, Ian, at OCI
  Biology and experimental therapy of solid tumors: biological properties of solid tumors, influence of environmental factors on cell membrane exchange mechanisms and susceptibility of therapeutic attack.
• Trudel, Suzanne, at OCI
  Molecular Targeted Therapy for the Treatment of Multiple Myeloma
• Tsao, Ming, at OCI
  Molecular biology and pathogenesis of lung and pancreatic cancers.
• van der Kooy, Derek, at Terrence Donnelly CCBR
• Wells, Richard, at SHSC
  Nuclear Receptors in Normal and Malignant Haematopoiesis
• Wong, Shun, at SHSC
  Response of the Central Nervous System to Ionizing Radiation.
• Woo, Minna, at OCI
  Tissue-specific Molecular Determinants of Survival, Apoptosis and Metabolism
• Woodgett, Jim R., at Mount Sinai Hospital
  Signal transduction; transcriptional regulation; molecular biology and gene expression.
• Zacksenhaus, Eldad, at Canadian Blood Service Building

Advanced Medical Discovery Institute (AMDI), Hospital for Sick Children (HSC), Medical Sciences Building (MSB), Ontario Cancer Institute (OCI), Sunnybrook Health Sciences Centre (SHSC), Toronto Medical Discovery Tower (TMDT)