MBP 1015Y Graduate Student Seminars

*Note: Please provide your seminar titles as soon as possible to Daphne Sears (daphne.sears@utoronto.ca). Titles need to be available at least 6 weeks prior to your seminar date so it is desirable to have them available at the start of the seminar series.

The primary goals of the MBP Student Seminar Series (course MBP1015Y) are to provide the student with practical experience and guidance for clear and concise oral communication of research results to an audience of educated non-specialists. This is an essential skill for anyone seeking a career in scientific research and beyond.  This emphasis differs from that of a group meeting or conference style talk given to an audience of specialists; here, the student presents to a diverse interdisciplinary group of peers, so familiarity with the field, its details, its specialized terms and abbreviations CANNOT be assumed.  This may be more analogous to a job talks or a teaching situation, where getting the essential points across and engaging the audience are key.  In this year's seminars, all speakers should expect a particularly broad audience with the mixture and uptown and downtown physics and biology talks.

A secondary important goal of the series is to give each student a broad knowledge of all aspects of research undertaken in MBP. At any oral examination and committee meeting, a student can be asked to demonstrate some familiarity with research in the Department not related to his/her own area. Attendance at the Student Seminars is the principal means of acquiring this familiarity.

An engaged, interested, interactive audience is essential to the success of MBP1015Y, hence ask questions. We will note attendance at both sites through the seminar evaluation forms each attending student fills out.  Non-participating students can face marks deduction at the end of the academic year.

It is very important to get regular attendance from a significant number of faculty members, to ensure consistent and fair evaluations. Please attend and interact with colleagues whenever possible (ideally every week). There is compelling evidence that the mark a student receives in this course is correlated with the attendance record of the supervisor.  So please lead by example!  

Following the seminars, the faculty members remain in the seminar room for a brief evaluation period that provides direct feedback to the presenters.  The discussion is led by the course coordinators, Drs. Alex Vitkin and Michael Hoffman for the downtown location and Dr. Brad MacIntosh at Sunnybrook.  2nd year MSc and PhD students will receive a mark providing the basis for the grade on their transcript. As mentioned above, good faculty participation, comprising in and out of stream members, is important to ensure a fair and robust evaluation process.

For information on the preparation of seminars, please consult the guidelines posted on the MBP website: Seminar Guidelines

Miscellaneous points of note:

  • Both auditoria are available half an hour before the start of the seminar onwards to provide ample time for presenters to test computer equipment and presentation material prior to going live.
  • First year MSc students will give a practice seminar towards the end of the winter term; the schedule for these will be posted in early 2018.  Also a training session will be announced at that time. 
  • Post-docs, technicians, clinical collaborators and other interested staff are welcome to take part
  • It is extremely rude and disruptive for any attendee to enter late and/or leave early. Please remain for the entire session (two to three speakers) if possible

Seminar Guidelines

Abstract Submission:
Concise abstracts (~ 250 words) should be provided similar to an abstract for a poster at a scientific conference. The name of the supervisor should be included on the abstract. All speakers should Email their abstracts to Daphne Sears (daphne.sears@utoronto.ca) on the Friday before your seminar. All students are asked to use the templates below when preparing their abstracts. Abstracts should not be over 1 page long.

***Please note that abstracts received after the deadline will NOT be circulated***

Abstract Template - Sunnybrook

Abstract Template - Downtown

Shuttle Bus Schedule

Evaluation form to be used by faculty

Evaluation form to be used by students


September | October | November | December | January | February | March | April | May | June|

Sunnybrook: Tuesdays at 4:00 PM. 
Sunnybrook, 2075 Bayview Avenue, Jenkin Auditorium, Rm TB-21*

Downtown: Wednesdays at 4:00 PM. 
Princess Margaret Cancer Centre Auditorium, 610 University Avenue, Room 6-604

Schedule - 2018-2019

Seminar date Student Seminar Title Supervisor
Wed. September 26, 2018 Introductory talk: Dr. Michael Hoffman
Zsuzsa Lindenmaier Co-clinical trials of autism in mice and humans- an update Lerch
Tue. October 2, 2018  Introductory talk: Dr. Brad MacIntosh
Yonni Friedlander

Rapid, Spectrally Resolved MRI of Hyperpolarized 129Xe Dissolved in the Rat Brain

Wed. October 3, 2018  Michael Atkins Modeling human embryonic hematopoietic development with pluripotent stem cells Keller
 Justin Burgener

Investigating the Clinical Utility of ctDNA Epigenetic Changes in Head and Neck Squamous Carcinoma

Tue. October 9, 2018  Datta Goolaub Rapid 3D imaging of fetal blood circulation with MRI Macgowan
 Ali Madani Tonekaboni Development of computational pipelines to optimize cancer drug development and drug-patient matching Haibe-Kains/Lupien
Wed. October 10, 2018  Sara Zarabi

ClpP activation: A novel therapeutic strategy for hematologic malignancies

 Jennifer Gottwald

Physics-based scatter correction for quantitative PET imaging of hypoxia

Tue. October 16, 2018  Parasvi Patel RNF168 deficiency confers synthetic lethality in BRCA1/2mutant tumors through impairment of R-loop resolution Hakem
 Pirashaanthy Tharmapalan

The Progesterone-Calcitonin Pathway in the Adult Mammary Gland and Breast Cancer

Wed. October 17, 2018 Stanley Zhou

Noncoding single-nucleotide variants target FOXA1 cis-regulatory elements in primary prostate cancer

 Meghan Lambie Identification and preclinical assessment of radiosensitizing drugs for squamous cell carcinomas Bratman
Tue. October 23, 2018        **Location Change: SG22  Mikko Hyvarinen Computer Simulations for Applications of Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids Hynynen
Mattea Welch Radiomic and RTx-omic Features for Prediction of Cancer Treatment Response Jaffray
Wed. October 24, 2018  Jenny Lou The Use of Porphyrin Nanoparticles to Enhance Adoptive Cell Therapy Zheng
 Laura Richards   Pugh
Tue. October 30, 2018  Casey Lee

Hyperpolarized 13C-MRI of the Human Brain

 Maryam Motmaen Dadgar The Effect of Material Thicknesses and Properties on the performance and Acoustic Power of Multilayer Ultrasound Transducers Hynynen
Wed. October 31, 2018  Hui Guo

Structures and dynamics of ATP synthases

Ariana Rostami Rapid release of ctDNA as a biomarker of treatment response in preclinical models of head and neck squamous cell carcinoma Bratman
Tue. November 6, 2018  Samir Barghout

The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target in acute myeloid leukemia

 Jenna van Leeuwen

Identifying synthetic lethal potentiators of statins targeting the metabolic mevalonate pathway as anti-breast cancer agents

Wed. November 7, 2018  Carly Pellow Investigating nonlinear porphyrin-bubble behaviour for vascular and extravascular applications Goertz/Zheng
James Pemberton Understanding the pro-apoptotic mechanism of Puma in neuronal cell destruction Andrews
Tue. November 13, 2018 Jordan Chad

Microscopic Free Water Content: A Novel Biomarker of Brain Aging


Antoine Beauchamp

Exploring Anxiety in Neurodevelopmental Disorders using Cross-Species Neuroimaging Analytics


Wed. November 14, 2018

Cornelia Redel

role of epigenetic regulators on MYC transcriptional activity in MYC-dependent tumorigenesis


Anum Rahman

Mechanism of brain abnormalities in complex congenital cardiac defects


Tue. November 20, 2018

Aaron Botham

Mapping the protein interactome of mitochondrial intermembrane space proteases identifies a novel function for HTRA2

Mitchell Doughty

MRI Driven Augmented Reality Image Guidance Platform for Myocardial Cell Delivery

Wed.  November 21, 2018 Lauren Podmore

Toward understanding the interaction between the insulin receptor and the ErbB family


Cindy Yang

Characterizing factors of response and resistance to immune checkpoint inhibitor in metastatic solid tumours and microenvironments

Tue. November 27, 2018 Christopher Huynh

Fetal Cardiac MR Imaging with Metric Optimized Gating and Deep Learning

Dang Nguyen Investigating the molecular mechanism underlying Bim-mediated Bax activation using in vitro assays and patient-derived dermal fibroblasts Andrews
Wed. November 28, 2018  Vinayak Bhandari The Clinico-Genomics of Prostate Cancer Hypoxia Bristow
Luke Chung

Brain temperature regulation in a preclinical model of repeated mild traumatic brain injury

Tue. December 4, 2018 Raymond Chen Elucidation of the role of histone modifiers and other druggable targets in the viral mimicry response de Carvalho
Azin Esmaelbeigi Quantitative Mapping of Cerebrovascular Reactivity Using Resting-State fMRI Chen
Wed. December 5, 2018 Danielle Denisko Motif elucidation in ChIP-seq datasets with a knockout control Hoffman
Amanda Khoo

Proteomics of urine-derived extracellular vesicles for prostate cancer biomarker discovery

Tue. December 11, 2018 Matt Hemsley Synthetic-CTs with uncertainty estimates using deep learning Lau
Greg Kuling Breast Cancer Risk Prediction using Magnetic Resonance Imaging in Women of High Risk Martel
Wed. December 12, 2018 Katharina Fritsch

Proteomics of Prostate Proximal Fluids to Detect Variations between Prostate Cancer Risk Groups

Soroush Ghomaschi

The Impact of Radiofrequency Ablation on Bone Quality in The Metastatically Involved Spine

Tue. December 18, 2018 Hao Li The Effects of Rapamycin on the Brain Lerch
Jennifer Lou Electron cryomicroscopy of fatty acid biosynthesis enzymes in yeast Mazhab Jafari
Wed. December 19, 2018 Camilla Giovino

Modeling the pharmacologic prevention of cancer in Li-Fraumeni Syndrome

Ian Fernandes   Keller
Winter 2019
Tue. January 8, 2019        **Location Change: M6-502 Joshua Miller   Hakem
Petr Smirnov   Haibe-Kains/Pugh
Wed. January 9, 2019 Alannah MacDonald MYC Phosphorylation Regulates Oncogenic Activity Penn
Jessica Petricca   He
Tue. January 15, 2019 Meghan Wing   Chakrabartty
Nadia Bragagnolo Metabolic Imaging of the Human Heart using Hyperpolarized [1,2-13C]Pyruvate Cunningham
Wed. January 16, 2019 Ian Smith   Haibe-Kains
Celina Li

Pre-clinical validation of transrectal diffuse optical tomography for monitoring photocoagulation progression during photothermal therapy

Tue. January 22, 2019 Saqeeb Hassan   Wright
Kevin Kiezun Ultrasound-stimulated microbubble indentation of saturated poroelastic media Goertz
Wed. January 23, 2019   Downtown Seminar cancelled
Tue. January 29, 2019 Matthew Ng   Wright
Yi Lin   Hynynen
Wed. January 30, 2019 Fupan Yao Tumor Heterogeneity of Atypical Teratoid Rhabdoid Tumors Huang
Nili Yuen

Characterizing the effects of Fluoxetine and Metformin on brain development following cranial irradiation

Tue. February 5, 2019 Nicholas Luciw   MacIntosh
Geoffrey Klein   Martel
Wed. February 6, 2019 Helen Zhu   Reimand
Valli Subasri Predictive modeling of cancer-type in Li-Fraumeni syndrome Malkin
Tue. February 12, 2019 Felipe Roa Garcia

Microultrasound and Photoacoustic Imaging for Improved Detection of Neoplastic Lesions in the Esophagus

Melissa Prickaerts   Akens
Wed. February 13, 2019 Christopher McFadden   Lilge
Oliver Ocsenas   Reimand
Tue. February 19, 2019 Nidhi Singh   Demore
Paige Smith   O'Reilly
Wed. February 20, 2019   Downtown Seminar cancelled  
Wed. February 27, 2019 Andrea Tench Regulation of the CBL E3 Ubiquitin Ligase by Src-Like Adaptor Proteins McGlade
Michael Woolman   Zarrine-Afsar
Wed. March 6, 2019 Daniel Molenhuis

Treatment Planning Considerations for Interstitial Photodynamic Therapy of High-Grade Glioma

Jared Westreich   Vitkin