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MBP 1015Y Graduate Student Seminars

*Note: Please provide your seminar titles as soon as possible to Daphne Sears ( Titles need to be available at least 6 weeks prior to your seminar date so it is desirable to have them available at the start of the seminar series.

The primary goals of the MBP Student Seminar Series (course MBP1015Y) are to provide the student with practical experience and guidance for clear and concise oral communication of research results to an audience of educated non-specialists. This is an essential skill for anyone seeking a career in scientific research and beyond.  This emphasis differs from that of a group meeting or conference style talk given to an audience of specialists; here, the student presents to a diverse interdisciplinary group of peers, so familiarity with the field, its details, its specialized terms and abbreviations CANNOT be assumed.  This may be more analogous to a job talks or a teaching situation, where getting the essential points across and engaging the audience are key.  In this year's seminars, all speakers should expect a particularly broad audience with the mixture and uptown and downtown physics and biology talks.

A secondary important goal of the series is to give each student a broad knowledge of all aspects of research undertaken in MBP. At any oral examination and committee meeting, a student can be asked to demonstrate some familiarity with research in the Department not related to his/her own area. Attendance at the Student Seminars is the principal means of acquiring this familiarity.

An engaged, interested, interactive audience is essential to the success of MBP1015Y, hence ask questions. We will note attendance at both sites through the seminar evaluation forms each attending student fills out.  Non-participating students can face marks deduction at the end of the academic year.

It is very important to get regular attendance from a significant number of faculty members, to ensure consistent and fair evaluations. Please attend and interact with colleagues whenever possible (ideally every week). There is compelling evidence that the mark a student receives in this course is correlated with the attendance record of the supervisor.  So please lead by example!  

Following the seminars, the faculty members remain in the seminar room for a brief evaluation period that provides direct feedback to the presenters.  The discussion is led by the course coordinators, Drs. Alex Vitkin and Michael Hoffman for the downtown location and Dr. Brad MacIntosh at Sunnybrook.  2nd year MSc and PhD students will receive a mark providing the basis for the grade on their transcript. As mentioned above, good faculty participation, comprising in and out of stream members, is important to ensure a fair and robust evaluation process.

For information on the preparation of seminars, please consult the guidelines posted on the MBP website: Seminar Guidelines

Miscellaneous points of note:

  • Both auditoria are available half an hour before the start of the seminar onwards to provide ample time for presenters to test computer equipment and presentation material prior to going live.
  • First year MSc students will give a practice seminar towards the end of the winter term; the schedule for these will be posted in early 2018.  Also a training session will be announced at that time. 
  • Post-docs, technicians, clinical collaborators and other interested staff are welcome to take part
  • It is extremely rude and disruptive for any attendee to enter late and/or leave early. Please remain for the entire session (two to three speakers) if possible

Seminar Guidelines

Abstract Submission:
Concise abstracts (~ 250 words) should be provided similar to an abstract for a poster at a scientific conference. The name of the supervisor should be included on the abstract. All speakers should Email their abstracts to Daphne Sears ( on the Friday before your seminar. All students are asked to use the templates below when preparing their abstracts. Abstracts should not be over 1 page long.

***Please note that abstracts received after the deadline will NOT be circulated***

Abstract Template - Sunnybrook

Abstract Template - Downtown

Shuttle Bus Schedule

Evaluation form to be used by faculty

Evaluation form to be used by students


September | October | November | December | January | February | March | April | May | June|

Sunnybrook: Tuesdays at 4:00 PM. 
Sunnybrook, 2075 Bayview Avenue, Jenkin Auditorium, Rm TB-21*

Downtown: Wednesdays at 4:00 PM. 
Princess Margaret Cancer Centre Auditorium, 610 University Avenue, Room 6-604

Schedule - 2017-18

Fall 2017
Wednesday, September 27 Introductory session
Tuesday, October 3 Introductory session
Date Student Title Supervisor
Wednesday, October 04 Hua, Tony (Jun Jie) Regulation and function of lncRNA PCAT19 in prostate cancer He
Jaiswal, Arushi Therapeutic targeting of TRB3 and USP9x in basal-like breast cancer Reedijk
Tuesday, October 10 Reguera Nunez, Elaine

Preclinical impact of nintedanib, an antiangiogenic TKI, combined with chemotherapy and/or immune checkpoint therapy in primary or metastatic triple negative breast cancer

Feng, Shengrui Characterization of the Anti-Tumour Effects of EZH2 Inhibition in Atypical Teratoid Rhabdoid Tumours de Carvalho
Wednesday, October 11 Kubli, Shawn

Deciphering the role of Toso (Fcmr) in regulating the immune response during oncogenesis

Longo, Joseph Exploiting statins as anti-cancer agents Penn
Tuesday, October 17 Wan, Ho Yee Evaluating microvascular dysfunction after experimental subarachnoid hemorrhage Hynynen
Atwi, Sarah Advanced applications of fMRI for the study of cerebral small vessel disease MacIntosh
Wednesday, October 18 Mazrooei, Parisa Mutational landscape in prostate cancer and its role on transcription factors' activity Lupien
Sun, Yulong Modulation of TDP-43 phase separation Chakrabartty
Tuesday, October 24 McMahon, Dallan Exploring the impact of focused ultrasound and microbubbles on brain microvasculature Hynynen
Santos, Marc

MRI-guided focused ultrasound hyperthermia with microbubbles for liposomal doxorubicin delivery at reduced power levels

Wednesday, October 25 Paramathas, Sangeetha

Using ctDNA for early cancer detection in a pre-clinical model of Li-Fraumeni Syndrome

Quevedo, Rene

Shallow whole genome copy number profiling to authenticate genomic identity

Tuesday, October 31 Shirzadi, Zahra Enhancement of automated blood flow estimates MacIntosh
Croucher, Danielle Single Cell Transcriptional Analysis of the Bone Marrow Microenvironment in Multiple Myeloma Trudel/Pugh
Wednesday, November 01 Resetca, Diana Characterizing the Interactomes of the Myc Family of Oncoproteins Penn/Raught
Zhang, Alice (Yangjing) Understanding the isoform specific functions of Numb in tumour and normal development McGlade
Tuesday, November 07 Salcedo, Adriana

RB1 genotype drives the mutational landscape and evolution of retinoblastoma

Dobri, Simon

Measuring GABA concentration in the human auditory cortex using in vivo magnetic resonance spectroscopy

Wednesday, November 08 Miyata, Tsukiko Investigation of the role of GSK3 in synaptic plasticity Woodgett
Shi, Kelly (Ruoshi) Therapeutic targeting of the PI3K pathway in lung squamous cell carcinoma Tsao

Tuesday, November 14*
*(change of location: Harrison Hall, Room EG21)

Coles, Brandon Increasing the RF safety of Cardiovascular Interventional Devices during MRI using Parallel Radiofrequency Transmission Wright
Assimopoulos, Stephania Advanced MRI Methods for Assessment of Placental Dysfunction and Fetal Distress Sled
Wednesday, November 15 Houlahan, Kathleen Germline polymorphisms direct the prostate cancer methylome Boutros
Law, Jacqueline An Orthotopic CRISPR Screen for Determinants of Head and Neck Cancer Metastasis F-F Liu
Tuesday, November 21 Mouraviev, Andrei

Automated Segmentation of Brain Metastases

Fletcher, Stecia Multi-frequency Ultrasound Strategies for Creating a Controlled Focus for Blood-Spinal Cord Barrier (BSCB) Opening O'Reilly
Wednesday, November 22 Karimzadeh Reghbati, Mehran

Virtual ChIP-seq: predicting transcription factor binding by learning from the transcriptome

Loo Yau, Helen Transcriptional programs linking IRF7 signalling to enhanced cytolytic activity are modulated by 5-AZA-CdR in CD8+ T cells de Carvalho
Tuesday, November 28 Riberdy, Vlora

Hyperpolarized 129Xe Imaging of Alveolar-Like Macrophages in the Lungs Using Superparamagnetic Iron-Oxide Nanoparticles

Gibson, Christopher

Development and clinical translation of a new handheld imaging device for 5-ALA fluorescence guided breast conserving surgery

Wednesday, November 29 Walton, Joseph

Targeting Epigenetic Regulation in Clear Cell Renal Cell Carcinoma Background/Purpose

Chen, Sujun

Transcriptome characterization and functional annotation for circRNA in prostate cancer

Tuesday, December 05 Oglesby, Ryan

CEST MRI: Investigation into the Biosynthesis Pathway of Serotonin

Geady, Caryn

Physiological Basis of CT-Derived Radiomics Classifiers and their link to Hypoxia

Wednesday, December 06 Isaev, Karin Discovery and characterization of clinically relevant lncRNAs in multiple cancer types Reimand
Nguyen, Francis

Predicting genomic annotation from chromatin accessibility experiments

Tuesday, December 12 Seth, Nikhil

Automated Detection of DCIS in Whole Slide Images

Toma, Jonathan

 Intracardiac Echo (ICE) & Computed Tomography (CT) Co-Registration for the Purpose of Guiding Percutaneous Cardiovascular Interventions

Wednesday, December 13 Grant, Benjamin

Biophysical characterization of KRas regulation by the calcium binding protein calmodulin

Kelly, Jacalyn

Investigating a functional assay and single-cell hypermutation detection for reliably detecting Constitutional Mismatch Repair Deficiency Syndrome

Tuesday, December 19 Xu, Rui

Focusing Ultrasound to the Vertebral Canal

Wei, Luxi (Lucy)

Direct measurement of Blood Flow Reflections by Ultrasound

Wednesday, December 20 Othman, Kamal Identifying signaling pathways associated with the misregulation of Numb isoform expression in cancer McGlade
Hawley, James

Assessing epigenomic heterogeneity through DNA methylation entropy

Winter 2018
Wednesday, January 03 Mahendralingam, Mathepan

Exploiting the metabolic dependencies of mammary epithelial subsets

Ivanochko, Danton

The Structural and Functional Elucidation of PRDM Proteins

Tuesday, January 9 Yang, Jing Array-based Dual Frequency Ultrasound Imaging for Acoustic Angiography Demore
Zhao, Xiaoxiao

Investigating ultrasound mediated vascular disruption in tumors

Wednesday, January 10 Ladumor, Yagnesh Investigating the Role of Vitamin D Receptor in Metastatic Neuroblastoma Irwin
Poon, Stephanie Characterizing the role of carcinoma-associated fibroblasts in head and neck squamous cell carcinoma cell invasion Ailles
Tuesday, January 16 Esmaelbeigi, Azin

Quantitative mapping of cerebrovascular reactivity using resting-state BOLD fMRI

Ocsenas, Oliver

Using deep learning methods on multivariate -omics datasets to analyze clinical characteristics of tumors

Wednesday, January 17 Psarianos, Pamela

Targeting FOXO1 to Reverse Radiation Fibrosis

Samuel, Timothy

Improving our understanding of the in vivo effects of stereotactic body radiation therapy (SBRT) on the perivascular microenvironment of pancreatic tumors

Tuesday, January 23 Petricca, Jessica

 Identifying circular RNA prognostic markers for prostate cancer using non-invasive liquid biopsy. 

Prickaerts, Melissa Effects of Ultrafast Lasers on Skeletal Tissues for Orthopaedic Surgery Akens
Wednesday, January 24 Su, Peiran

Functional genomic screening with lung cancer patient-derived xenograft models

Yang, Donghe

Modeling the development of human ventricular cardiomyocyte lineages using human embryonic stem cells

Tuesday, January 30 Kuling, Gregory

Risk assessment and Radiomics of Magnetic Resonance Breast Screening using Machine Learning

Subasri, Vallijah Modeling Age of Onset and Tumor Type in Li-Fraumeni Syndrome Malkin
Wednesday, January 31 Podmore, Lauren Toward understanding the interaction between the insulin receptor and the ErbB family Stambolic
Redel, Cornelia A strategic approach to target oncogenic MYC Penn
Smith, Ian

Discovering Biomarkers for Drug Sensitivity in Cell Lines using DNA Methylation Data

Tuesday, February 6 Beauchamp, Antoine Examining the Comorbidity of Anxiety in Neurodevelopmental Disorders Lerch
Bragagnolo, Nadia

Characterizing Heart Failure by the Measurement of Metabolites in the Myocardium using Hyperpolarized 13C MRI

Wednesday, February 7 Woolman, Michael Identification of Medulloblastoma Subgroups On Intrasurgical Timescales With Picosecond Infrared Laser Desorption Mass Spectrometry Zarrine-Afsar
Zarabi, Sara

Hyperactivation of the human mitochondrial protease ClpP in acute myeloid leukemia

Zhu, Helen Driver Mutations in Prostate Cancer Reimand
Tuesday, February 13 Chad, Jordan

Diffusion MRI of aging brain microstructure: Characterizing 'free water'

Wednesday, February 14 Chen, Raymond Characterizing the functional and biological effects of targeting protein arginine methyltransferase 5 de Carvalho
Chung, Luke

Brain temperature regulation in a preclinical model of repeated mild traumatic brain injury

Denisko, Danielle Motif elucidation in ChIP-seq datasets with a knockout control Hoffman
Tuesday, February 20 Doughty, Mitchell MRI driven augmented reality guidance system for targeted cardiac stem cell procedures Ghugre
Ghomaschi, Soroush

The Impact of Radiofrequency Ablation on Bone Quality in Metastatically Involved Spine

Wednesday, February 21 Fernandes, Ian   Keller
Fritsch, Katharina Proteomics of prostate proximal fluids for the identification of aggressive disease Kislinger
Giovino, Camilla Modelling Pharmacologic Prevention of Cancer in Li-Fraumeni Syndrome Malkin
Tuesday, February 27 Hassan, Saqeeb Improving the Characterization of Cardiac Infarct Heterogeneity Using Motion-Resolved T1 Mapping Wright
Hemsley, Matt Pseudo CT using conditional generative adversarial neural networks for MRI-guided radiotherapy Lau
Wednesday, February 28 Khoo, Amanda Ultra-low cell proteomics for characterizing mammary stem and progenitor cell populations Kislinger
Kissoon, Randolph

Examining the role of Mitochondrial DNA Mutations in Acute Myeloid Leukemia Initiation & Progression

Li, Hao The Effects of Rapamycin on the Brain Lerch
Tuesday, March 6 Huynh, Christopher

Undersampled MR image reconstruction with deep learning: application in fetal MRI

Lin, Yi

Passive Acoustic Monitoring of Microbubbles in Ultrasound Induced Blood-brain Barrier Opening

Wednesday, March 7 Lou, Jennifer Electron cryo-microscopy characterization of amino acid sensing protein GCN2 Mazhab-Jafari
Luciw, Nicholas Resting-state functional brain connectivity with arterial spin labelled MRI MacIntosh
McFadden, Christopher

Treatment of Peripheral Lung Cancer with Photodynamic Therapy

Tuesday, March 13 Ng, Matthew Quantifying Uncertainties in Neural Networks for Cardiac MR Segmentation Wright
Roa Garcia, Felipe

Microultrasound and Photoacoustic Imaging for Improved Staging of Dysplasia and Adenocarcinoma in the Esophagus

Wednesday, March 14 MacDonald, Alannah

MYC Phosphorylation Regulates Oncogenic Activity

Miller, Joshua

Chromatin modifying CRISPR screen in BRCA2 mutant ovarian cancer

Tench, Andrea

Characterizing Tyrosine Kinase Signaling Networks in Leukemia

Tuesday, March 20 Singh, Nidhi

Transrectal Photoacoustic Imaging (TR-PAI) for detection and localization of Prostate Index Tumor for Photothermal Therapy (PTT)

Smith, Paige

Active control of focused ultrasound for blood-spinal cord barrier disruption and drug delivery

Wednesday, March 21 Wing, Meghan

Detection of light chain amyloidosis in plasma cell dyscrasias using conformation-specific polyclonal antibodies

Yao, Fupan Tumor Heterogeneity of Atypical Teratoid Rhabdoid Tumors Huang
Kiezun, Kevin

Ultrasound-stimulated microbubble induced fluid transport in poroelastic media

Tuesday, March 27 Westreich, Jared

Polarimetry feature extraction for breast cancer margin assessment

Klein, Geoffrey

Stability Estimation for Vertebral Compression Fracture from Spinal Metastases

Wednesday, March 28 Smirnov, Petr

Evaluating the Utility of Preclinical Pharmacogenomic Screens to Inform Precision Medicine Research

Li, Liyao

Photocoagulation front monitoring using diffuse optical tomography and photoacoustic imaging during porphysome-enabled photothermal therapy for prostate cancer

Yuen, Nili Characterizing the effects of Fluoxetine and Metformin on neurogenesis following cranial irradiation Nieman
Tuesday, April 3      
Molenhuis, Daniel Photodynamic therapy treatment planning for the glioma patient Lilge

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