MBP 1015Y Graduate Student Seminars

*Note: Please provide your seminar titles as soon as possible to Daphne Sears (daphne.sears@utoronto.ca). Titles need to be available at least 6 weeks prior to your seminar date so it is desirable to have them available at the start of the seminar series.

The primary goals of the MBP Student Seminar Series (course MBP1015Y) are to provide the student with practical experience and guidance for clear and concise oral communication of research results to an audience of educated non-specialists. This is an essential skill for anyone seeking a career in scientific research and beyond.  This emphasis differs from that of a group meeting or conference style talk given to an audience of specialists; here, the student presents to a diverse interdisciplinary group of peers, so familiarity with the field, its details, its specialized terms and abbreviations CANNOT be assumed.  This may be more analogous to a job talks or a teaching situation, where getting the essential points across and engaging the audience are key.  In this year's seminars, all speakers should expect a particularly broad audience with the mixture and uptown and downtown physics and biology talks.

A secondary important goal of the series is to give each student a broad knowledge of all aspects of research undertaken in MBP. At any oral examination and committee meeting, a student can be asked to demonstrate some familiarity with research in the Department not related to his/her own area. Attendance at the Student Seminars is the principal means of acquiring this familiarity.

An engaged, interested, interactive audience is essential to the success of MBP1015Y, hence ask questions. We will note attendance at both sites through the seminar evaluation forms each attending student fills out.  Non-participating students can face marks deduction at the end of the academic year.

It is very important to get regular attendance from a significant number of faculty members, to ensure consistent and fair evaluations. Please attend and interact with colleagues whenever possible (ideally every week). There is compelling evidence that the mark a student receives in this course is correlated with the attendance record of the supervisor.  So please lead by example!  

Following the seminars, the faculty members remain in the seminar room for a brief evaluation period that provides direct feedback to the presenters.  The discussion is led by the course coordinators, Drs. Alex Vitkin and Michael Hoffman for the downtown location and Dr. Brad MacIntosh at Sunnybrook.  2nd year MSc and PhD students will receive a mark providing the basis for the grade on their transcript. As mentioned above, good faculty participation, comprising in and out of stream members, is important to ensure a fair and robust evaluation process.

For information on the preparation of seminars, please consult the guidelines posted on the MBP website: Seminar Guidelines
 

Miscellaneous points of note:

  • Both auditoria are available half an hour before the start of the seminar onwards to provide ample time for presenters to test computer equipment and presentation material prior to going live.
  • First year MSc students will give a practice seminar towards the end of the winter term; the schedule for these will be posted in early 2018.  Also a training session will be announced at that time. 
  • Post-docs, technicians, clinical collaborators and other interested staff are welcome to take part
  • It is extremely rude and disruptive for any attendee to enter late and/or leave early. Please remain for the entire session (two to three speakers) if possible

Seminar Guidelines

Abstract Submission:
Concise abstracts (~ 250 words) should be provided similar to an abstract for a poster at a scientific conference. The name of the supervisor should be included on the abstract. All speakers should Email their abstracts to Daphne Sears (daphne.sears@utoronto.ca) on the Friday before your seminar. All students are asked to use the templates below when preparing their abstracts. Abstracts should not be over 1 page long.

***Please note that abstracts received after the deadline will NOT be circulated***

Abstract Template - Sunnybrook

Abstract Template - Downtown

Shuttle Bus Schedule

Evaluation form to be used by faculty

Evaluation form to be used by students

 

September | October | November | December | January | February | March | April | May | June|

Sunnybrook: Tuesdays at 4:00 PM. 
Sunnybrook, 2075 Bayview Avenue, Jenkin Auditorium, Rm TB-21*

Downtown: Wednesdays at 4:00 PM. 
Princess Margaret Cancer Centre Auditorium, 610 University Avenue, Room 6-604

Schedule - 2018-2019

Seminar date

Student

Seminar Title

Supervisor

Wed. September 26, 2018

Introductory talk: Dr. Michael Hoffman

Zsuzsa Lindenmaier

Co-clinical trials of autism in mice and humans- an update

Lerch

Tue. October 2, 2018

Introductory talk: Dr. Brad MacIntosh

Yonni Friedlander

Rapid, Spectrally Resolved MRI of Hyperpolarized 129Xe Dissolved in the Rat Brain

Santyr

Wed. October 3, 2018

 Michael Atkins

Modeling human embryonic hematopoietic development with pluripotent stem cells

Keller

 Justin Burgener

Investigating the Clinical Utility of ctDNA Epigenetic Changes in Head and Neck Squamous Carcinoma

Bratman

Tue. October 9, 2018

 Datta Goolaub

Rapid 3D imaging of fetal blood circulation with MRI

Macgowan

 Ali Madani Tonekaboni

Development of computational pipelines to optimize cancer drug development and drug-patient matching

Haibe-Kains

Wed. October 10, 2018

Sarah Zarabi

ClpP activation: A novel therapeutic strategy for hematologic malignancies

Schimmer

 Jennifer Gottwald

Physics-based scatter correction for quantitative PET imaging of hypoxia

Jaffray

Tue. October 16, 2018

 Parasvi Patel

RNF168 deficiency confers synthetic lethality in BRCA1/2mutant tumors through impairment of R-loop resolution

Hakem

 Pirashaanthy Tharmapalan

The Progesterone-Calcitonin Pathway in the Adult Mammary Gland and Breast Cancer

Khokha

Wed. October 17, 2018

Stanley Zhou

Noncoding single-nucleotide variants target FOXA1 cis-regulatory elements in primary prostate cancer

Lupien

 Meghan Lambie

Identification and preclinical assessment of radiosensitizing drugs for squamous cell carcinomas

Bratman

Tue. October 23, 2018

**Location Change: SG22

 Mikko Hyvarinen

Computer Simulations for Applications of Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids

Hynynen

Mattea Welch

Radiomic and RTx-omic Features for Prediction of Cancer Treatment Response

Jaffray

Wed. October 24, 2018

 Jenny Lou

The Use of Porphyrin Nanoparticles to Enhance Adoptive Cell Therapy

Zheng

 Laura Richards

Single-cell analysis of subclonal heterogeneity in glioblastoma and brain tumour stem cells

Pugh

Tue. October 30, 2018

 Casey Lee

Hyperpolarized 13C-MRI of the Human Brain

Cunningham

 Maryam Motmaen Dadgar

The Effect of Material Thicknesses and Properties on the performance and Acoustic Power of Multilayer Ultrasound Transducers

Hynynen

Wed. October 31, 2018

Hui Guo

Structures and dynamics of ATP synthases

Bratman

Ariana Rostami

Rapid release of ctDNA as a biomarker of treatment response in preclinical models of head and neck squamous cell carcinoma

Rubinstein

Tue. November 6, 2018

 Samir Barghout

The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target in acute myeloid leukemia

Schimmer

 Jenna van Leeuwen

Identifying synthetic lethal potentiators of statins targeting the metabolic mevalonate pathway as anti-breast cancer agents

Penn

Wed. November 7, 2018

 Carly Pellow

Investigating nonlinear porphyrin-bubble behaviour for vascular and extravascular applications

Zheng

James Pemberton

Understanding the pro-apoptotic mechanism of Puma in neuronal cell destruction

Andrews

Tue. November 13, 2018

Jordan Chad

Microscopic Free Water Content: A Novel Biomarker of Brain Aging

Schimmer

Antoine Beauchamp

A Cross-Study Data Analytic Approach to Identifying Neuroanatomical Signatures of Anxiety in Neurodevelopmental Disorders

Lerch

Wed. November 14, 2018

Cornelia Redel

Determining the role of epigenetic regulators in MYC-driven cancers

Penn

Anum Rahman

How does an abnormal heart affect the newborn brain?

Sled

Tue. November 20, 2018

 Aaron Botham

 

Chen

Mitchell Doughty

MRI Driven Augmented Reality Guidance System for Targeted Cardiac Procedures

Ghugre

Wed.  November 21, 2018

 Lauren Podmore

Toward understanding the interaction between the insulin receptor and the ErbB family

Stambolic

Cindy Yang

Understanding factors of response and resistance to immune checkpoint inhibitor in metastatic solid tumours and microenvironments

Pugh

Tue. November 27, 2018

Christopher Huynh

Fetal Cardiac MR Imaging with Metric Optimized Gating and Deep Learning

Macgowan

Dang Nguyen

Investigating the molecular mechanism underlying Bim-mediated Bax activation using in vitro assays and patient-derived dermal fibroblasts

Andrews

Wed. November 28, 2018

Vinayak Bhandari

The Clinico-Genomics of Prostate Cancer Hypoxia

Bristow

Luke Chung

Brain temperature regulation in a preclinical model of repeated mild traumatic brain injury

Sled

Tue. December 4, 2018

Raymond Chen

Elucidation of the role of histone modifiers and other druggable targets in the viral mimicry response

de Carvalho

Azin Esmaelbeigi

Quantitative Mapping of Cerebrovascular Reactivity Using Resting-State fMRI

Chen

Wed. December 5, 2018

Danielle Denisko

Motif elucidation in ChIP-seq datasets with a knockout control

Hoffman

Amanda Khoo

Proteomics of urine-derived extracellular vesicles for prostate cancer biomarker discovery

Kislinger

Tue. December 11, 2018

Matt Hemsley

Synthetic-CTs with uncertainty estimates using deep learning

Lau

Greg Kuling

Breast Cancer Risk Prediction using Magnetic Resonance Imaging in Women of High Risk

Martel

Wed. December 12, 2018

Katharina Fritsch

Proteomics of Prostate Proximal Fluids to Detect Variations between Prostate Cancer Risk Groups

Kislinger

Soroush Ghomaschi

The Impact of Radiofrequency Ablation on Bone Quality in The Metastatically Involved Spine

Akens

Tue. December 18, 2018

Hao Li

The Effects of Rapamycin on the Brain

Lerch

Jennifer Lou

Using electron cryo-microscopy to study the inner workings of fatty acid synthase

Mazhab Jafari

Wed. December 19, 2018

Camilla Giovino

 

Malkin

Ian Fernandes

Modelling Human Cardiac Development and Disease in the Petri Dish

Keller

2019

Tue. January 8, 2019 

**Location Change: M6-502

Joshua Miller

Exploiting synthetic lethal relationships of BRCA1/2 for ovarian cancer therapy

Hakem

Petr Smirnov

Evaluating the Utility of Preclinical Pharmacogenomic Screens to Inform Precision Medicine Research

Haibe-Kains/Pugh

Wed. January 9, 2019

Alannah MacDonald

MYC Phosphorylation Regulates Oncogenic Activity

Penn

Jessica Petricca

Identifying multi-model prognostic markers for prostate cancer using non-invasive liquid biopsy

He

Tue. January 15, 2019

Meghan Wing

Detection of light chain amyloidosis in plasma cell dyscrasias using conformation-specific antibodies

Chakrabartty

Nadia Bragagnolo

Metabolic Imaging of the Human Heart using Hyperpolarized [1,2-13C]Pyruvate

Cunningham

Wed. January 16, 2019

Ian Smith

Predicting Cancer Drug Sensitivity with a Latent Space Model of DNA Methylation in Cell Lines

Haibe-Kains

Celina Li 

Pre-clinical validation of transrectal diffuse optical tomography for monitoring photocoagulation progression during photothermal therapy

Wilson

Tue. January 22, 2019

Saqeeb Hassan

Improving the Characterization of Cardiac Infarct Heterogeneity Using Motion-Resolved T1 Mapping

Wright

Kevin Kiezun

Ultrasound-stimulated microbubble indentation of saturated poroelastic media

Goertz

Wed. January 23, 2019

Downtown Seminar cancelled

Tue. January 29, 2019

Matthew Ng

Estimating Uncertainty in Neural Networks for Segmentation Quality Control

Wright

Yi Lin

Passive Acoustic Monitoring of Microbubbles in Ultrasound Induced Blood-brain Barrier Opening

Hynynen

Wed. January 30, 2019

Fupan Yao

Tumor Heterogeneity of Atypical Teratoid Rhabdoid Tumors

Huang

Nili Yuen

Characterizing the effects of Fluoxetine and Metformin on brain development following cranial irradiation

Nieman

Tue. February 5, 2019

Nicholas Luciw

Cerebral perfusion covariance mapping to study differences between adolescents with and without bipolar disorder 

MacIntosh

Geoffrey Klein

Stability Estimation for Vertebral Compression Fracture from Spinal Metastases

Martel

Wed. February 6, 2019

Helen Zhu

Driver discovery in primary localized prostate cancer

Reimand

Vallijah Subasri

Predictive modeling of cancer-type in Li-Fraumeni syndrome

Malkin

Tue. February 12, 2019

  Sunnybrook Seminar Cancelled  

Wed. February 13, 2019

Christopher McFadden

Treatment Planning for Peripheral Lung Cancer with Photodynamic Therapy

Lilge

Oliver Ocsenas

Examining genomic and epigenomic features shaping the mutational landscape of cancer

Reimand

Tue. February 19, 2019
(3:00 - 5:00 pm)

Felipe Roa Garcia

Microultrasound and Photoacoustic Imaging for Improved Detection of Neoplastic Lesions in the Esophagus

Demore

Melissa Prickaerts

Analysis of Ultrafast Burst Mode Laser Ablation on Articular Cartilage

Akens

Paige Smith

Active control of focused ultrasound for blood-spinal cord barrier disruption and drug delivery

O'Reilly

Nidhi Singh

Photoacoustic Imaging for detection and localization of Prostate Index Tumor for Photothermal Therapy (PTT)

Demore

Wed. Feb 20, 2019

Downtown Seminar cancelled

Tue. February 26, 2019

Khajehim, Mahdi

Mapping Brain Microvasculature using Magnetic Resonance Fingerprinting

Chen

Tan, Ziyu

Magnetization transfer of prostate cancer

Stanisz

Wed. Feb. 27, 2019

Andrea Tench

Regulation of the CBL E3 Ubiquitin Ligase by Src-Like Adaptor Proteins

McGlade

Michael Woolman

 

Zarrine-Afsar

Tue. Mar 5, 2019

Chen, Jianan

Characterizing Tumor Heterogeneity using Radiogenomics

Martel

Cook, Moses

Mending a Broken Heart: Image Based Response Monitoring of Stem Cell-Derived Cardiomyocyte Engraftment Post MI 

Ghugre

Wed. March 6, 2019

Daniel Molenhuis

Treatment Planning Considerations for Interstitial Photodynamic Therapy of High-Grade Glioma

Lilge

Jared Westreich

 

Vitkin

Tue. March 12, 2019

Ciga, Ozan

Multiclass Classification of Breast Cancer in Whole Slide Images

Martel

Dagys. Megan

Investigating the changes in oligodendrocyte density in brain regions following CRT using QSM

Nieman

Wed. March 13, 2019

Chen, Jocelyn

 

Lupien

Cowen, Justin

 

Rottapel

Cruise, Edward

 

Stambolic

Tue. March 19, 2019

Debebe, Sarah

 

Sled

Eric Wang

Investigating the immune response as an approach to improve treatment of high-risk prostate cancer

Bailey

Wed. March 20, 2019

Dhaliwal, Alexander

Overcoming Obstacles in Cancer Nanomedicine Delivery using a Versatile In Situ Ultrasound-Triggered Microbubble-to-Nanoparticle Conversion

Zheng

Fiering, Quinton

Exploring Metabolic Enzyme Interactions in Cancer Epigenetics

Raught

Ge, Sabrina

Transcriptional heterogeneity in pancreatic cancer and its role in chemoresistance

Notta

Tue. March 26, 2019

Huang, Rui

 

Wright

Lin, Zhongmin

Functional magnetic resonance imaging and electroencephalography of neuropsychological tests

Graham

Wed. March 27, 2019

Ha, Cindy

Tuning the RADIIO: Radiation, Inflammasome, and Immunotherapy

Harding

Hendrikse, Liam

Integrative Genomics of Group 4 Medulloblastoma

Taylor

Liu, Lydia Yiyang

The Timing and Origin of Lymph Node Metastasis in Head and Neck Cancer

Reimand

Tue. April 2, 2019

Martin, David

 

O'Reilly

Patel, Jayakumar

Real-time Respiratory Heart Motion Correction for MRI-Guided Cardiac Interventions

Wright

Wed. April 3, 2019

Jones, Blake

 

Vitkin

Katz, Lauren

Picosecond InfraRed Laser Mass Spectrometry for Rapid Detection of Melanoma and Melanoma Mimicking Lesions

Zarrine-Afsar

Hummel, Lauren

The role of genome doubling in metastatic progression of pancreatic ductal adenocarcinoma (PDAC)".

Notta

Tue. April 9, 2019

Tan, Josephine

Assessment of aberrant metabolism using deuterium magnetic resonance spectroscopy

Lau

Djayakarsana, Daniel

Modeling and Classifying Tumour Microenvironment with Quantitative MRI

Liu

Wed. April 10, 2019

Lee, Christian

 

Reimand

Liu, Ningdi Feng

Mechanisms of RAS-mediated activation of RAF kinases at the cell membrane

Ikura

Majeed, Safa

 

Liu

Tue. April 16, 2019

Yuen Nicole

 

Graham

Keimakh, Denis

 

Haibe-Kains

Wed. April 17, 2019

Medina Cruz, Alison

Characterizing the mutant PAX5 and IKZF1 interactomes by BioID

Raught

Munidasa, Samal

 

Santyr

Nguyen, Quynh

 

Keller

Tue. April 23, 2019

Marsilla, Joseph

 

Haibe-Kains

Skarsgard, Matthew

 

Sled

Wed. April 24, 2019

Rasnitsyn, Alexandra

Uncovering the molecular mechanisms behind sex bias in paediatric Ependymoma

Taylor

Telfer, Frank

 

Malkin

Teng, Mona

 

He

Tue. April 30, 2019

Fliss, Jordan

 

4th rotation

Zhuo, Gareth Jingran

 

4th rotation

Wed. May 1, 2019

Walker, Wesley

Radioisotope-Loaded Texaphyrin-Lipid Nanoparticles as Theragnostic Agents

Zheng

Wang, Evan Yifan

The transcriptional landscape of WNT Medulloblastoma

Taylor

Woollard, Geoffrey

 

Mazhab-Jafari/Ikura

Wed. May 8, 2019

Yang, Yitong

 

Chan

Yanofsky, David

 

Rubinstein

Yoo, Kimoon

Phase-shift porphyrin nanodroplet mediated sonodynamic therapy

Zheng

Wed. May 15, 2019

Yu, Johnson

 

Stefanovic

De Michino, Steven

 

4th rotation

Jin, Helen Jingshu

Understanding the Interaction of AML with the Bone Marrow Microenvironment: Elucidating New Therapeutic Targets Through In Vivo Imaging

4th rotation

Wed. May 22, 2019

Downtown Seminar cancelled

Wed. May 29, 2019

Patel, Aesha

 

4th rotation