MBP 1015Y Graduate Student Seminars

*Note: Please provide your seminar titles to Daphne Sears (daphne.sears@utoronto.ca) within 2 weeks after you are advised of your scheduled date. Titles can be changed later if necessary. 

The primary goals of the MBP Student Seminar Series (course MBP1015Y) are to provide the student with practical experience and guidance for clear and concise oral communication of research results to an audience of educated non-specialists. This is an essential skill for anyone seeking a career in scientific research and beyond.  This emphasis differs from that of a group meeting or conference style talk given to an audience of specialists; here, the student presents to a diverse interdisciplinary group of peers, so familiarity with the field, its details, its specialized terms and abbreviations CANNOT be assumed.  This may be more analogous to a job talks or a teaching situation, where getting the essential points across and engaging the audience are key.  In this year's seminars, all speakers should expect a particularly broad audience with the mixture and uptown and downtown physics and biology talks.

A secondary important goal of the series is to give each student a broad knowledge of all aspects of research undertaken in MBP. At any oral examination and committee meeting, a student can be asked to demonstrate some familiarity with research in the Department not related to his/her own area. Attendance at the Student Seminars is the principal means of acquiring this familiarity.

An engaged, interested, interactive audience is essential to the success of MBP1015Y, hence ask questions. We will note attendance at both sites through the seminar evaluation forms each attending student fills out.  Non-participating students can face marks deduction at the end of the academic year.

It is very important to get regular attendance from a significant number of faculty members, to ensure consistent and fair evaluations. Please attend and interact with colleagues whenever possible (ideally every week). There is compelling evidence that the mark a student receives in this course is correlated with the attendance record of the supervisor.  So please lead by example!  

Following the seminars, the faculty members remain in the seminar room for a brief evaluation period that provides direct feedback to the presenters.  The discussion is led by the course coordinator, Dr. Michael Hoffman for the downtown location and Dr. Brad MacIntosh at Sunnybrook.  2nd year MSc and PhD students will receive a mark providing the basis for the grade on their transcript. As mentioned above, good faculty participation, comprising in and out of stream members, is important to ensure a fair and robust evaluation process.

For information on the preparation of seminars, please consult the guidelines posted on the MBP website: Seminar Guidelines

Miscellaneous points of note:

  • Both auditoria are available half an hour before the start of the seminar onwards to provide ample time for presenters to test computer equipment and presentation material prior to going live.
  • First year MSc students will give a practice seminar towards the end of the winter term; the schedule for these will be posted in early 2018.   
  • Post-docs, technicians, clinical collaborators and other interested staff are welcome to take part
  • It is extremely rude and disruptive for any attendee to enter late and/or leave early. Please remain for the entire session (two to three speakers) if possible

Seminar Guidelines

Abstract Submission:
Concise abstracts (~ 250 words) should be provided similar to an abstract for a poster at a scientific conference. The name of the supervisor should be included on the abstract. All speakers should Email their abstracts to Daphne Sears (daphne.sears@utoronto.ca) on the Thursday before your seminar. All students are asked to use the templates below when preparing their abstracts. Abstracts should not be over 1 page long.

***Please note that abstracts received after the deadline will NOT be circulated***

Abstract Template - Sunnybrook

Abstract Template - Downtown

Shuttle Bus Schedule

Evaluation form to be used by faculty

Evaluation form to be used by students


September | October | November | December | January | February | March | April | May | June|

Sunnybrook: Tuesdays at 4:00 PM. 
Sunnybrook, 2075 Bayview Avenue, Jenkin Auditorium, Rm TB-21*

Downtown: Wednesdays at 4:00 PM. 
Princess Margaret Cancer Centre Auditorium, 610 University Avenue, Room 6-604

Schedule - 2018-2019

Seminar date Student Seminar Title Supervisor
Wed. September 26, 2018 Introductory talk: Dr. Michael Hoffman
Zsuzsa Lindenmaier Co-clinical trials of autism in mice and humans- an update Lerch
Tue. October 2, 2018  Introductory talk: Dr. Brad MacIntosh
Yonni Friedlander Rapid, Spectrally Resolved MRI of Hyperpolarized 129Xe Dissolved in the Rat Brain Santyr
Wed. October 3, 2018  Michael Atkins Modeling human embryonic hematopoietic development with pluripotent stem cells Keller
 Justin Burgener Investigating the Clinical Utility of ctDNA Epigenetic Changes in Head and Neck Squamous Carcinoma Bratman
Tue. October 9, 2018  Datta Goolaub Rapid 3D imaging of fetal blood circulation with MRI Macgowan
 Ali Madani Tonekaboni Development of computational pipelines to optimize cancer drug development and drug-patient matching Haibe-Kains
Wed. October 10, 2018 Sarah Zarabi ClpP activation: A novel therapeutic strategy for hematologic malignancies Schimmer
 Jennifer Gottwald Physics-based scatter correction for quantitative PET imaging of hypoxia Jaffray
Tue. October 16, 2018  Parasvi Patel RNF168 deficiency confers synthetic lethality in BRCA1/2mutant tumors through impairment of R-loop resolution Hakem
 Pirashaanthy Tharmapalan The Progesterone-Calcitonin Pathway in the Adult Mammary Gland and Breast Cancer Khokha
Wed. October 17, 2018 Stanley Zhou Noncoding single-nucleotide variants target FOXA1 cis-regulatory elements in primary prostate cancer Lupien
 Meghan Lambie Identification and preclinical assessment of radiosensitizing drugs for squamous cell carcinomas Bratman
Tue. October 23, 2018     **Location Change: SG22  Mikko Hyvarinen Computer Simulations for Applications of Magnetic Resonance Guided Focused Ultrasound Surgery (MRgFUS) of Uterine Fibroids Hynynen
Mattea Welch Radiomic and RTx-omic Features for Prediction of Cancer Treatment Response Jaffray
Wed. October 24, 2018  Jenny Lou The Use of Porphyrin Nanoparticles to Enhance Adoptive Cell Therapy Zheng
 Laura Richards Single-cell analysis of subclonal heterogeneity in glioblastoma and brain tumour stem cells Pugh
Tue. October 30, 2018  Casey Lee Hyperpolarized 13C-MRI of the Human Brain Cunningham
 Maryam Motmaen Dadgar The Effect of Material Thicknesses and Properties on the performance and Acoustic Power of Multilayer Ultrasound Transducers Hynynen
Wed. October 31, 2018 Hui Guo Structures and dynamics of ATP synthases Bratman
Ariana Rostami Rapid release of ctDNA as a biomarker of treatment response in preclinical models of head and neck squamous cell carcinoma Rubinstein
Tue. November 6, 2018  Samir Barghout The ubiquitin-activating enzyme, UBA1, as a novel therapeutic target in acute myeloid leukemia Schimmer
 Jenna van Leeuwen Identifying synthetic lethal potentiators of statins targeting the metabolic mevalonate pathway as anti-breast cancer agents Penn
Wed. November 7, 2018  Carly Pellow Investigating nonlinear porphyrin-bubble behaviour for vascular and extravascular applications Zheng
James Pemberton Understanding the pro-apoptotic mechanism of Puma in neuronal cell destruction Andrews
Tue. November 13, 2018 Jordan Chad Microscopic Free Water Content: A Novel Biomarker of Brain Aging Schimmer
Antoine Beauchamp A Cross-Study Data Analytic Approach to Identifying Neuroanatomical Signatures of Anxiety in Neurodevelopmental Disorders Lerch
Wed. November 14, 2018 Cornelia Redel Determining the role of epigenetic regulators in MYC-driven cancers Penn
Anum Rahman How does an abnormal heart affect the newborn brain? Sled
Tue. November 20, 2018  Aaron Botham   Chen
Mitchell Doughty MRI Driven Augmented Reality Guidance System for Targeted Cardiac Procedures Ghugre
Wed.  November 21, 2018  Lauren Podmore Toward understanding the interaction between the insulin receptor and the ErbB family Stambolic
Cindy Yang Understanding factors of response and resistance to immune checkpoint inhibitor in metastatic solid tumours and microenvironments Pugh
Tue. November 27, 2018 Christopher Huynh Fetal Cardiac MR Imaging with Metric Optimized Gating and Deep Learning Macgowan
Dang Nguyen Investigating the molecular mechanism underlying Bim-mediated Bax activation using in vitro assays and patient-derived dermal fibroblasts Andrews
Wed. November 28, 2018 Vinayak Bhandari The Clinico-Genomics of Prostate Cancer Hypoxia Bristow
Luke Chung Brain temperature regulation in a preclinical model of repeated mild traumatic brain injury Sled
Tue. December 4, 2018 Raymond Chen Elucidation of the role of histone modifiers and other druggable targets in the viral mimicry response de Carvalho
Azin Esmaelbeigi Quantitative Mapping of Cerebrovascular Reactivity Using Resting-State fMRI Chen
Wed. December 5, 2018 Danielle Denisko Motif elucidation in ChIP-seq datasets with a knockout control Hoffman
Amanda Khoo Proteomics of urine-derived extracellular vesicles for prostate cancer biomarker discovery Kislinger
Tue. December 11, 2018 Matt Hemsley Synthetic-CTs with uncertainty estimates using deep learning Lau
Greg Kuling Breast Cancer Risk Prediction using Magnetic Resonance Imaging in Women of High Risk Martel
Wed. December 12, 2018 Katharina Fritsch Proteomics of Prostate Proximal Fluids to Detect Variations between Prostate Cancer Risk Groups Kislinger
Soroush Ghomaschi The Impact of Radiofrequency Ablation on Bone Quality in The Metastatically Involved Spine Akens
Tue. December 18, 2018 Hao Li The Effects of Rapamycin on the Brain Lerch
Jennifer Lou Using electron cryo-microscopy to study the inner workings of fatty acid synthase Mazhab Jafari
Wed. December 19, 2018 Camilla Giovino

Modeling the pharmacologic prevention of cancer in Li-Fraumeni Syndrome

Ian Fernandes Modelling Human Cardiac Development and Disease in the Petri Dish Keller
Tue. January 8, 2019    **Location Change: M6-502 Joshua Miller Exploiting synthetic lethal relationships of BRCA1/2 for ovarian cancer therapy  Hakem
Petr Smirnov Evaluating the Utility of Preclinical Pharmacogenomic Screens to Inform Precision Medicine Research Haibe-Kains/Pugh
Wed. January 9, 2019 Alannah MacDonald MYC Phosphorylation Regulates Oncogenic Activity Penn
Jessica Petricca Identifying multi-model prognostic markers for prostate cancer using non-invasive liquid biopsy He
Tue. January 15, 2019 Meghan Wing Detection of light chain amyloidosis in plasma cell dyscrasias using conformation-specific antibodies Chakrabartty
Nadia Bragagnolo Metabolic Imaging of the Human Heart using Hyperpolarized [1,2-13C]Pyruvate Cunningham
Wed. January 16, 2019 Ian Smith Predicting Cancer Drug Sensitivity with a Latent Space Model of DNA Methylation in Cell Lines Haibe-Kains
Celina Li   Pre-clinical validation of transrectal diffuse optical tomography for monitoring photocoagulation progression during photothermal therapy Wilson
Tue. January 22, 2019 Saqeeb Hassan Improving the Characterization of Cardiac Infarct Heterogeneity Using Motion-Resolved T1 Mapping Wright
Kevin Kiezun Ultrasound-stimulated microbubble indentation of saturated poroelastic media Goertz
Wed. January 23, 2019 Downtown Seminar cancelled
Tue. January 29, 2019 Matthew Ng Estimating Uncertainty in Neural Networks for Segmentation Quality Control Wright
Yi Lin Passive Acoustic Monitoring of Microbubbles in Ultrasound Induced Blood-brain Barrier Opening  Hynynen
Wed. January 30, 2019 Fupan Yao Tumor Heterogeneity of Atypical Teratoid Rhabdoid Tumors Huang
Nili Yuen Characterizing the effects of Fluoxetine and Metformin on brain development following cranial irradiation Nieman
Tue. February 5, 2019 Nicholas Luciw Cerebral perfusion covariance mapping to study differences between adolescents with and without bipolar disorder  MacIntosh
Geoffrey Klein Stability Estimation for Vertebral Compression Fracture from Spinal Metastases Martel
Wed. February 6, 2019   Downtown Seminar cancelled  
Tue. February 12, 2019 Sunnybrook Seminar cancelled
Wed. February 13, 2019 Christopher McFadden Treatment Planning for Peripheral Lung Cancer with Photodynamic Therapy Lilge
Oliver Ocsenas Examining genomic and epigenomic features shaping the mutational landscape of cancer Reimand
Tue. February 19, 2019 Felipe Roa Garcia Microultrasound and Photoacoustic Imaging for Improved Detection of Neoplastic Lesions in the Esophagus Demore
Melissa Prickaerts Analysis of Ultrafast Burst Mode Laser Ablation on Articular Cartilage Akens
Paige Smith Active control of focused ultrasound for blood-spinal cord barrier disruption and drug delivery O'Reilly
Nidhi Singh Photoacoustic Imaging for detection and localization of Prostate Index Tumor for Photothermal Therapy (PTT) Demore
Wed. Feb 20, 2019 Downtown Seminar cancelled
Tue. February 26, 2019 Khajehim, Mahdi Mapping Brain Physiology using Magnetic Resonance Fingerprinting Chen
Tan, Ziyu Early Prediction of Prostate Cancer Treatment Response Using Saturation Transfer Stanisz
Wed. Feb. 27, 2019 Andrea Tench Regulation of the CBL E3 Ubiquitin Ligase by Src-Like Adaptor Proteins McGlade
Michael Woolman

A hand-held Picosecond Infra Red Laser Probe for Rapid Intrasurgical Classification of Pediatric Brain Tumours with Mass Spectrometry

Tue. Mar 5, 2019 Chen, Jianan Characterizing Tumor Heterogeneity using Radiogenomics Martel
Cook, Moses

MRI Response Monitoring of Stem Cell-Derived Cardiomyocyte Engraftment Post Myocardial Infarction

Wed. March 6, 2019 Daniel Molenhuis

Photodynamic Therapy (PDT): accessing efficacy determining parameters for glioblastoma multiforme (GBM)

Jared Westreich

Polarized Light Imaging of Human Breast Cancer

Tuesday, March 12, 2019 Ciga, Ozan Multiclass Classification of Breast Cancer in Whole Slide Images Martel
Dagys. Megan Investigating the changes in oligodendrocyte density in brain regions following CRT using QSM Nieman
Wednesday, March 13, 2019 Chen, Jocelyn

Exploring the metabolic and epigenetic mechanisms underlying chemoresistance in triple-negative breast cancer

Cowen, Justin

Investigating stiffness-dependent activation of GEF-H1 in pancreatic ductal adenocarcinoma

Cruise, Edward

Proteomic Characterization of PTEN Functional Mutants

Tuesday, March 19, 2019 Debebe, Sarah

Microcomputed Tomography and ultrasound characterization of uterine artery wave reflections

Eric Wang Investigating the immune response as an approach to improve treatment of high-risk prostate cancer S. Liu
Wednesday, March 20, 2019 Dhaliwal, Alexander Overcoming Obstacles in Cancer Nanomedicine Delivery using a Versatile In Situ Ultrasound-Triggered Microbubble-to-Nanoparticle Conversion Zheng
Ge, Sabrina Transcriptional heterogeneity in pancreatic cancer and its role in chemoresistance and metastasis Notta
Tuesday, March 26, 2019 Huang, Rui

Automatic blood vessel segmentation for guiding percutaneous vascular interventions

Lin, Zhongmin Functional Magnetic Resonance Imaging and Electroencephalography of Neuropsychological Tests Graham
Wednesday, March 27, 2019 Ha, Cindy Tuning the RADIIO: Radiation, Inflammasome, and Immunotherapy Harding
Hendrikse, Liam Integrative Genomics of Group 4 Medulloblastoma Taylor
Liu, Lydia Yiyang

The Timing and Origin of Lymph Node Metastasis in Head and Neck Cancer

Tuesday, April 2, 2019 Martin, David

Adaptive Treatment Planning for Focused Ultrasound in the Human Vertebral Canal

Patel, Jayakumar

Real-time Respiratory Heart Motion Correction for MRI-Guided Cardiac Interventions

Wednesday, April 3, 2019 Jones, Blake

Blood flow alteration in irradiated tissues: an automated pipeline for segmentation, skeletonization and analysis of OCT-derived microvascular maps

Katz, Lauren

Picosecond InfraRed Laser-Mass Spectrometry for Rapid Detection of Melanoma and Melanoma Mimicking Lesions

Hummel, Lauren

The Role of Tetraploidy in Metastatic Progression of Pancreatic Ductal Adenocarcinoma

Tuesday, April 9, 2019 Tan, Josephine

Deuterium (2H) Magnetic Resonance Spectroscopy (MRS) of Brain Metastases

Djayakarsana, Daniel

Modifying and Classifying Tumour Microenvironment with Quantitative MRI

Wednesday, April 10, 2019 Lee, Christian Examining genetic interactions of driver mutations in whole cancer genomes Reimand
Liu, Ningdi Feng Mechanisms of RAS-mediated activation of RAF kinases at the cell membrane Ikura
Majeed, Safa Targeting a ubiquitin-activating enzyme in small cell lung cancer Liu
Tuesday, April 16, 2019 Yuen Nicole The Effect of Age in Distracted Driving Using fMRI and Eye-tracking   Graham
Keimakh, Denis An investigation into novel gene fusions using comparative analysis and drug response data Haibe-Kains
Wednesday, April 17, 2019 Medina Cruz, Alison Characterizing the mutant PAX5 and IKAROS interactomes by BioID Raught
Munidasa, Samal

Automated Image Analysis Pipeline for Quantitative Analysis of Ventilation Defects in Cystic Fibrosis

Nguyen, Quynh  Patterning human hematopoietic development using pluripotent stem cells Keller
Tuesday, April 23, 2019 Marsilla, Joseph   Haibe-Kains
Skarsgard, Matthew

Chemical Exchange Saturation Transfer for Predicting Altered Brain Development Following Neonatal Hypoxic-Ischemic Encephalopathy

Wednesday, April 24, 2019 Rasnitsyn, Alexandra Sex effects in the molecular landscape of Posterior Fossa Type A Ependymoma Taylor
Telfer, Frank Investigating the Immunological Status of Li-Fraumeni Syndrome Malkin
Jin, Helen Jingshu Understanding the Interaction of AML with the Bone Marrow Microenvironment: Elucidating New Therapeutic Targets Through In Vivo Imaging DaCosta & Minden
Tuesday, April 30, 2019 Sunnybrook Seminar cancelled
Wednesday, May 1, 2019 Teng, Mona Functional characterization of RMST in neuroendocrine prostate cancer He
De Michino, Steven Exploration of Epigenetic Profiles in ctDNA to Identify Cancer Biomarkers Bratman
Woollard, Geoffrey Calcium signalling: structural insights of calcium channels from cryo-EM Mazhab-Jafari/Ikura
Wednesday, May 8, 2019 Yang, Yitong   Chan
Walker, Wesley Radioisotope-Loaded Texaphyrin-Lipid Nanoparticles as Theragnostic Agents Zheng
Yoo, Kimoon Phase-shift porphyrin nanodroplet mediated sonodynamic therapy Zheng
Wednesday, May 15, 2019 Yu, Johnson   Stefanovic
Wang, Evan Yifan The transcriptional landscape of WNT Medulloblastoma Taylor
Yanofsky, David   Rubinstein
Wednesday, May 22, 2019 Zhu, Helen

Driver Discovery in Primary Localized Prostate Cancer

Subasri, Valli

Predictive modeling of cancer-type in Li-Fraumeni syndrome

Wednesday, May 29, 2019 Patel, Aesha   Wouters
Fliss, Jordan   Santyr